张涛  副研究员  

研究方向:

电子邮件:zhangtao@sibet.ac.cn

电       话:0512-69588050

通讯地址:苏州市高新区科技城科灵路88号

简       历:

张涛,副研究员,20126月进入中国科学院苏州生物医学工程技术研究所工作,历任研究实习员、助理研究员、副研究员。主要从事微流控体外诊断试剂研制和三维细胞培养模型构建工作。主持医工结合项目、横向项目3项,参与国家重点研发计划、中科院装备研制项目、国家自然科学基金等多个项目。已发表论文SCI/EI论文13篇,授权专利10余项。

获奖及荣誉:

社会任职:

研究方向:

1)微流控体外诊断试剂研制:冻干试剂、数字PCR检测试剂研制

2)微流控三维细胞培养/肿瘤类器官模型构建

承担项目情况:

代表论著:

(1)  Zhang T*, Zhang H, Zhou W, Jiang K, Liu C, Wang R, Zhou Y, Zhang Z, Mei Q, Dong W*, Sun M*. Li H*. One-Step Generation and Purification of Cell-Encapsulated Hydrogel Microsphere With an Easily Assembled Microfluidic Device, Frontiers in Bioengineering and Biotechnology, 2022, 9: 816089

(2)  Zhang T*, Liu C, Zhou W, Jiang K, Yin C, Liu C, Zhang Z, Li H*. Ultrasensitive detection of Lead ions based on a DNAzyme and digital PCR. Journal of analytical methods in chemistry. 2019, 2019:1-6.

(3)  Zhang T#, Guo W#, Yang Y, Liu W, Guo L, Gu Y, Shu Y, Wang L, Wu X, Hua Z, Ke Y, Sun Y*, Shen Y*, Xu Q*. Loss of SHP-2 activity in CD4+ T cells promotes melanoma progression and metastasis. Scientific Reports. 2013, 3: 2845. 

(4)  Zhao W#Zhang T#Qu B, Wu X, Zhu X, Meng F, Gu Y, Shu Y, Shen Y, Sun Y, Xu Q*. Sorafenib induces apoptosis in HL60 cells by inhibiting Src kinase-mediated STAT3 phosphorylation. Anti-Cancer Drugs. 2011, 22(1):79-88. (# co-first author)

(5)  Zhou W, Liu C, Zhang T, Jiang K, Li H, Zhang Z, Tang Y. Low Cost, Easily-Assembled Centrifugal Buoyancy-Based Emulsification and Digital PCR. Micromachines, 2022, 13(2): 171.

(6)  Sun J, Zhang Z, Liu C, Dai X, Zhou W, Jiang K, Zhang T, Yin J, Gao J, Yin H, Li H. Continuous in situ portable SERS analysis of pollutants in water and air by a highly sensitive gold nanoparticle-decorated PVDF substrate. Analytical and Bioanalytical Chemistry, 2021, 413(21): 5469-5482.

(7)  Liu C, Zhou W, Zhang T, Jiang K, Li H, Dong W. An automated approach to classification of duplex assay for digital droplet PCR. Journal of Bioinformatics and Computational Biology. 2018,3:1850003.

(8)  Li H*, Wu L, Zhou W, Jiang K, Fu W, Dong Y, Chen S, Liu C, Zhang T, Ding S, Duan S, Li Y, Microfluidic disk for the determination of human blood types, Microsystem Technologies, 2017, 1-7.

(9)  Guo Z, Zhang Z, Zhang W, Zhou L, Li H, Wang H, Andreazza-Vignolle C, Andreazza P, Zhao D, Wu Y, Wang Q, Zhang T, Jiang K. Color-Switchable, Emission -Enhanced Fluorescence Realized by Engineering C dot@C-dot Nanoparticles. ACS Appl. Mater. Interfaces. 2014, 6: 20700-20708.

(10) 周武平, 唐玉国, 黎海文, 蒋克明,刘聪,张涛,张志强. 高通量离心式液滴生成芯片设计.光学精密工程. 2020, 28(12): 2636-2645. 

(11) 刘聪, 董文飞, 蒋克明, 周武平, 张涛, 黎海文. 基于改进分水岭分割算法的致密荧光微滴识别中国光学. 2019, 12(4): 783-790.

(12) 刘聪,董文飞,张涛,周武平,蒋克明,黎海文,微滴式数字聚合酶链式反应系统中荧光微滴的分类,光学精密工程. 2018, 26(3): 647-653

(13) 何皓, 张涛, 姚佳, 李传宇, 周连群, 王毅, 李明宇, 黎海文, 董文飞. 用于藻毒素检测的分子印迹修饰表面等离子体共振传感. 光学精密工程. 2015, 23(3): 723-728.

申请专利

1张涛、黎海文、蒋克明、周武平、刘聪、张志强。一种复合凝胶微球的制备方法、复合凝胶微球及其应用  201910336793.7(公开)

2张涛、黎海文、蒋克明、周武平、刘聪。基于微滴和纳米荧光探针的胞内蛋白检测方法  201611149908.4 (授权)

3张涛、黎海文、周武平、刘聪、蒋克明、郭振。一种浓缩葡萄糖检测试剂冻干微球及其制备方法  201410437964.2 (授权)

4张涛、黎海文、周武平、刘聪、蒋克明、张志强。一种浓缩二氧化碳结合力检测试剂冻干微球及其制备方法  201410437748.8(授权)

5)黎海文、张涛、周武平、刘聪、蒋克明、印晨宇。用于核酸检测的多通道微滴检测芯片 201721116338.9(授权)