邢晓曼  副研究员  

研究方向:

电子邮件:xingxm@sibet.ac.cn

电       话:

通讯地址:苏州市高新区科技城科灵路88号

简       历:

先后在中国科学技术大学,宾夕法尼亚大学学习及从事科研工作,研究生阶段师从著名物理学家Arjun G. Yodh

主要从事生理参数测量可穿戴医疗设备研究,以血液动力学为背景、从临床实际需求出发,以关键技术为突破点,重点研究睡眠中动态生理参数(如动态血压)、糖尿病血管疾病的可穿戴多模态测量技术、核心参数提取以及基于临床大数据和人工智能的干预效果评估技术,从而构筑睡眠障碍及糖尿病整体化解决方案。

先后主持1项国家重点研发计划子课题1项双创人才计划;作为核心人员策划并参与1项国家重点研发计划及多项省市级项目。与首都医科大学附属安贞医院、协和医院及北京大学第六医院存在长期合作关系

获奖及荣誉:

东吴科技创新创业领军人才 2016

社会任职:

研究方向:

(1) 动态生理参数测量:利用电学、光学、血液动力学等实现可穿戴及零接触测量,借助人工智能、数据分析挖掘和信息融合技术,开展心血管疾病、糖尿病、睡眠障碍等患病风险预测、智能辅助诊断及预后预测研究,为临床决策提供个性化解决方案。

(2) 睡眠障碍监测及调控:融合睡眠心率、呼吸、血氧、体动等信息,实现零/低负荷睡眠测量,辅助睡眠障碍诊疗,开展基于光学及声学的睡眠调控前沿研究。

(3) 糖尿病监测及调控:基于心率变异性、动态血压、PEI等复合参数对糖尿病进展及并发症进行早期预警,通过物理及药物调控,研究糖尿病及并发症改善情况。

承担项目情况:

代表论著:

期刊论文:

1.         X. Xing, Z. Ma, M. Zhang, Y. Zhou, W. Dong, and M. Song, "An Unobtrusive and Calibration-free Blood Pressure Estimation Method using Photoplethysmography and Biometrics," Scientific Reports, vol. 9, p. 8611, 2019/06/13 2019.

2.         X. Xing, P. Xu, S. Chen, G. Yuan, J. Mo and M. Sun, "Spectrum-Based Calibration Method for Energy Discriminating CZT Detectors Using Commercial X-Ray Generators," in IEEE Transactions on Nuclear Science, vol. 64, no. 5, pp. 1128-1132, May 2017.

3.         X. M. Xing and M. S. Sun, "Optical blood pressure estimation with photoplethysmography and FFT-based neural networks," Biomedical Optics Express, 7(8), (2016).

4.         Yuguo Tang; Shouyan Wang; Yile Wang; Xiaoman Xing; Yong Yu; Wenfei Dong, "Bridging the Gap from Bench to Bedside: China Takes a New Look at Moving Innovative Health Care Ideas into the Marketplace," Pulse, IEEE , vol.5, no.1, pp.55,58, Jan.-Feb. 2014

5.         郁朋、代秋声、邢晓曼,大束流场发射阴极X 射线管的阳极设计研究,原子能科学技术,2014,486):1127-1131

6.         邢晓曼、代秋声,碳纳米管场发射阴极制备技术的最新进展,CT理论与应用研究,2013,221):181-194.

7.         Mesquita, R.C., Putt, M., Chandra, M., Yu, G., Xing, X., Han, S.W., Lech, G., Shang, Y., Durduran, T., Zhou, C., Yodh, A.G., and Mohler, E.R., Diffuse optical characterization of an exercising patient group with peripheral artery disease Journal of Biomedical Optics, 18(5), 057007 (2013)

8.         代秋声、徐品、邢晓曼CT X射线能谱滤过器的优化设计,CT理论与应用研究,201120(3): 331-338

9.         Theresa M. Busch, Xiaoman Xing, Guoqiang Yu, Arjun Yodh, E. Paul Wileyto, Hsing-Wen Wang, Turgut Durduran, Timothy C. Zhu, and Ken Kang-Hsin Wang. Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to photofrin photodynamic therapy, Photochemical & Photobiological Sciences August ,8(12) ,1683-1693 (2009)

10.     George J. Cerniglia, Nabendu Pore, Jeff H. Tsai, Susan Schultz, Rosemarie Mick, Regine Choe, Xiaoman Xing, Turgut Durduran, Arjun G. Yodh, Sydney M. Evans, Cameron J. Koch, Stephen M. Hahn, Harry Quon, Chandra M. Sehgal, William M. F. Lee, and Amit MaityEpidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy, PLoS ONE ,4(8) ,e6539 (2009)

会议论文:

11.     Xiaoman Xing, Guoqiang Yu, Turgut Durduran, Elizabeth Rickter, Arjun G. Yodh, Theresa M. BuschPatterns of intra-tumor heterogeneity in vascular response during photodynamic therapyIn SPIE Photonics West, San Jose, CA, 2009

12.      Xiaoman Xing, Emile R Mohler, Turgut Durduran, Chao Zhou, Gwen Lech, Arjun Yodh, Guoqiang YuDiffuse Light Quantification of Peripheral Artery Disease (PAD)OSA Biomedical Topical Meeting 2008

13.      Guoqiang Yu, Theresa M. Busche, Turgut Durduran, Chao Zhou, Xiaoman Xing, Timothy Zhu, Jarod C. Finlay, S. Bruce Malkowicz, Stephen M. Hahn, and Arjun G. YodhBlood Flow Responses to Photodynamic Therapy with Two Photosensitizers: Photofrin and Motexafin Lutetium (MLu)OSA Topical Meeting 2008

14.      Yu, Guoqiang; Ahn, Chulhyun; Xing, Xiaoman; Durduran, Turgut; Mohler, Emile R. III; Erdman, Frank; Yodh, Arjun G.; Salcido, RichardHeat and Cold on the Back Modulate Blood Flow in Distant Skeletal MusclesThe American College of Sports Medicine 2008

15.     X. Xing, E. R. Mohler, C. Zhou, T. Durduran, G. Lech, Y. Shi, R. Wilensky, J. Moore, A. G. Yodh, G. YuHemodynamic changes in diabetic pig muscle, SVM (Society for Vascular Medicine) Annual Meeting 2007

16.      Xiaoman Xing, Emile R Mohler, Turgut Durduran, Chao Zhou, Gwen Lech, Guoqiang Yu, Arjun G. YodhDiffuse light quantification of peripheral artery diseaseIn SPIE Photonics West, San Jose, CA, 2007

17.      Xiaoman Xing, Kijoon Lee, Regine Choe, and A. G. YodhOptimization of the Sourcedetector Geometry for Diffuse Optical Tomography OSA Biomedical Topical Meeting 2006

申请专利32项,其中发明专利19项,授权21项,其中发明专利12项。

代表性专利:

1.基于血液容积波的多光源探测器连续心率测量方法, 邢晓曼,董文飞,宋明轩,发明,受理,201910673063.6

2.压力可控的合体式智能健康指环,邢晓曼,发明,受理,201710269890.x

2.压力可控的分体式智能健康指环,邢晓曼,发明,受理,201710269879.3

3.压力可控的合体式智能健康指环,邢晓曼,实用新型,授权,201720431525.X

4.压力可控的分体式智能健康指环,邢晓曼,实用新型,授权,201720431532.X

5.无创连续血压测量装置,邢晓曼、 孙明山、雷恒波、徐雅洁、杨晓冬、彭义杰,实用新型,授权,专利号:201620618793.8

6.无创连续血压测量装置,邢晓曼、 孙明山、雷恒波、徐雅洁、杨晓冬、彭义杰,发明,授权,专利号:201610454021.X

7. 一种脑血流测量装置、系统及头盔,邢晓曼、戴亚康,授权,专利号:201620943986.0

8.一种能量分辨CT探测器的校准方法,邢晓曼、徐品、陈奭、袁刚、张寅、郑健、孙明山,发明,授权,专利号:201510240652.7

9.一种静态CT扫描仪系统及其扫描方法邢晓曼、代秋声,发明,授权,专利号:CN201110247455.X

10.一种静态CT扫描仪及其散射X光子校正方法,代秋声、徐品、邢晓曼,发明,授权,专利号:CN201210264323.2

11.X射线管 代秋声徐品邢晓曼, 发明,公开,专利号:CN201210352085.0

12.静态能量分辨CT扫描仪及其扫描方法,代秋声、邢晓曼、徐品、刘猛,发明,授权,专利号:CN201210211462.9

13.基于单光子计数器的近红外三维动态成像仪系统,邢晓曼,发明,授权,专利号:ZL201310084831.7

14.运动伪影消除装置及其消除运动伪影的方法,邢晓曼,吕铁军,发明,授权,专利号:ZL201310217219.2

15.非接触式成像系统及其成像方法,邢晓曼,吕铁军,董月芳,发明,授权,专利号:201410081281.8

16.一种CT前置滤线器孙明山邢晓曼,发明,公开,专利号:CN201410326441.0

17.基于有序生长纳米壁的大束流场发射阴极制造方法,邢晓曼、徐品、孙明山、曾维俊,发明,授权,专利号,201510411222.7

18.一种CT扫描装置,孙明山,邢晓曼,徐品,实用新型,授权,专利号:CN201520890894.6